Asymmetric transfer hydrogenation of unsaturated ketones; factors influencing 1,4- vs 1,2- regio- and enantioselectivity, and alkene vs alkyne directing effects
نویسندگان
چکیده
A detailed study has been completed on the asymmetric transfer hydrogenation (ATH) of a series enones using Ru(II) catalysts. Electron-rich rings adjacent to CO group reduce level reduction compared CC. The ATH reaction can readily discriminate between double and triple bonds ketones, reducing bond but leaving intact in major product.
منابع مشابه
Asymmetric Hydrogenation and Transfer Hydrogenation of Ketones
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ژورنال
عنوان ژورنال: Tetrahedron
سال: 2021
ISSN: ['0040-4020', '1464-5416']
DOI: https://doi.org/10.1016/j.tet.2020.131771